货号：07-515

品牌：Merck Millipore

规格：

目录价：￥4376.00

市场价格：￥3719.60

会员价格：￥3500.80

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-p125Nap1 (Nck-associated protein 1) Antibody | 07-515 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Upstate (Millipore) View All» Specificity: p125Nap1 View All» Molecular Weight: 125kDa View All» Immunogen: Peptide corresponding to amino acids 1-16 of human p125Nap1. View All» Isotype: IgG View All» Species Reactivity: Human View All» Quality Assurance: Routinely evaluated by immunoblot on RIPA lysates from A431 cells. View All» Purification Method: Protein A chromatography View All» Presentation: 0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%. View All» Storage Conditions: 2 years at -20°C View All» UniProt Number: Q9Y2A7 View All» Entrez Gene Number: NM_205842 View All» Gene Symbol:

• NCKAP1

• FLJ11291

• NAP125

• NAP1

• p125Nap1

• KIAA0587

• HEM2

• MGC8981

• Nap1
  View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» UniProt Summary: FUNCTION: SwissProt: Q9Y2A7 # Is part of lamellipodial complex that controls Rac- dependent actin remodeling (By similarity).SIZE: 1128 amino acids; 128790 Da SUBUNIT: Associates preferentially with the first SH3 domain of NCK. Component of the WAVE2 complex composed of ABI1, CYFIP1/SRA1, NCKAP1/NAP1 and WASF2/WAVE2. Also a component of the WAVE1 complex composed of ABI2, CYFIP2, C3orf10/HSPC300, NCKAP1 and WASF1/WAVE1. CYFIP2 binds to activated RAC1 which causes the complex to dissociate, releasing activated WASF1. The complex can also be activated by NCK1 (By similarity).TISSUE SPECIFICITY: Expressed in all tissues examined except peripheral blood leukocytes, with highest expression in brain, heart, and skeletal muscle.SIMILARITY: SwissProt: Q9Y2A7 ## Belongs to the HEM-1/HEM-2 family. View All» Brand Family: Upstate View All» Product Name: Anti-p125Nap1 (Nck-associated protein 1) Antibody | 07-515 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 200 µg View All» Format: Purified View All» Host: Rabbit View All»
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