货号：07-531

品牌：Merck Millipore

规格：200Ug

目录价：￥6127.00

市场价格：￥5207.95

会员价格：￥4901.60

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-PIR121-1/Sra-1 Antibody | 07-531 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Upstate (Millipore) View All» Specificity: PIR121-1/Sra-1 (aka CYFIP1) View All» Molecular Weight: Mr~130kDa View All» Immunogen: KLH-conjugated, synthetic peptide corresponding to amino acids 872-886 (SQEFQRDKQPNAQPQ-C) of human PIR121-1/Sra-1, with a C-terminal cysteine added for conjugation purposes. View All» Isotype: IgG View All» Species Reactivity:

• Human

• Mouse
  View All» Quality Assurance: routinely evaluated by immunoblot on RIPA homogenates from rat brain View All» Purification Method: Protein A purfied View All» Storage Conditions: stable 2 years at -20°C from date of shipment View All» UniProt Number: Q96F07 View All» Entrez Gene Number: NM_014608 View All» Gene Symbol:
  • CYFIP2

  • KIAA1168

  • PIR121
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Immunoprecipitation

    • Western Blotting
      View All» UniProt Summary: FUNCTION: SwissProt: Q96F07 # Involved in T-cell adhesion and p53-dependent induction of apoptosis. Does not bind RNA.SIZE: 1278 amino acids; 148399 Da SUBUNIT: Interacts with FMR1, FXR1 AND FXR2. Component of the WAVE1 complex composed of ABI2, CYFIP2, C3orf10/HSPC300, NCKAP1 and WASF1/WAVE1. CYFIP2 binds to activated RAC1 which causes the complex to dissociate, releasing activated WASF1. The complex can also be activated by NCK1.SUBCELLULAR LOCATION: Cytoplasm. Cytoplasm, perinuclear region. Cell junction, synapse, synaptosome. Note=Highly expressed in the perinuclear region. Enriched in synaptosomes. Treatment with leptomycin-B triggers translocation to the nucleus.DISEASE:SwissProt: Q96F07 # Up-regulated significantly in CD4+ T lymphocytes from patients with multiple sclerosis (at protein level).SIMILARITY: SwissProt: Q96F07 ## Belongs to the CYFIP family. View All» Brand Family: Upstate View All» Product Name: Anti-PIR121-1/Sra-1 Antibody | 07-531 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 200 µg View All» Format: Purified View All» Host: Rabbit View All»
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