货号：07-561

品牌：Merck Millipore

规格：

目录价：￥5215.00

市场价格：￥4432.75

会员价格：￥4172.00

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-phospho-eNOS/NOS III (Ser617) Antibody | 07-561 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Upstate (Millipore) View All» Product Overview: Note: ADMA (Catalog #19-169) and NMMA (Catalog #19-170) are inhibitors of NOS View All» Specificity: phosphorylated eNOS/NOS III (Ser617) View All» Molecular Weight: 132kDa View All» Immunogen: Peptide corresponding to amino acids surrounding phosphorylated Ser617 of eNOS/NOS III. This site corresponds to human Ser615. View All» Modifications: Phosphorylation View All» Isotype: IgG View All» Species Reactivity: Bovine View All» Species Reactivity Note: The immunizing sequence has 11/12 identical amino acids in mouse, and canine. View All» Quality Assurance: routinely evaluated by immunoblot in RIPA lysates from fetal bovine heart endothelial (FBHE) cells View All» Purification Method: Immunoaffinity purified View All» Presentation: 0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30% View All» Storage Conditions: 1 year at -20°C View All» UniProt Number: P29474 View All» Entrez Gene Number: NM_000603 View All» Gene Symbol:

• NOS3

• cNOS

• ECNOS

• eNOS

• EC-NOS

• NOSIII
  View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» UniProt Summary: FUNCTION: SwissProt: P29474 # Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. No mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets.COFACTOR: Heme group. & Binds 1 FAD. & Binds 1 FMN. & Metrahydrobiopterin (BH4). May stabilize the dimeric form of the enzyme.SIZE: 1203 amino acids; 133289 Da SUBUNIT: Homodimer. Interacts with NOSIP and NOSTRIN.SUBCELLULAR LOCATION: Cell membrane, caveola. Cytoplasm, cytoskeleton. Golgi apparatus. Note=Specifically associates with actin cytoskeleton in the G2 phase of the cell cycle; which is favored by interaction with NOSIP and results in a reduced enzymatic activity.TISSUE SPECIFICITY: Platelets, placenta, liver and kidney.SIMILARITY: SwissProt: P29474 ## Belongs to the NOS family. & Contains 1 flavodoxin-like domain. View All» Brand Family: Upstate View All» Product Name: Anti-phospho-eNOS/NOS III (Ser617) Antibody | 07-561 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 200 µL View All» Format: Affinity Purified View All» Host: Rabbit View All»
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