货号：07-568

品牌：Merck Millipore

规格：EA

目录价：询价

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-phospho-c-Jun (Thr91) Antibody | 07-568 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Upstate (Millipore) View All» Specificity: phospho-c-Jun View All» Molecular Weight: 41kDa View All» Immunogen: peptide corresponding to amino acids 85-101 (NGHITT[pT]PTPTQFLCPK) of human c-jun View All» Modifications: Phosphorylation View All» Isotype: IgG View All» Species Reactivity:

• Human

• Mouse
  View All» Species Reactivity Note: Predicted to cross-react with rat and bovine based on sequence homology View All» Quality Assurance: routinely evaluated by immunoblot in RIPA lysates from 50mM cells that had been treated with anisomycin View All» Purification Method: Immunoaffinity purified View All» Presentation: 0.2M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30% View All» Storage Conditions: 1 year at -20°C View All» UniProt Number: P05412 View All» Entrez Gene Number: NM_010591 View All» Gene Symbol:
  • JUN

  • p39

  • AP1

  • c-Jun
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» Entrez Gene Summary: This gene is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies. View All» UniProt Summary: FUNCTION: SwissProt: P05412 # Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'.SIZE: 331 amino acids; 35676 Da SUBUNIT: Interacts with FOS to form a dimer. Interacts with SMAD3/SMAD4 heterodimers. Interacts with MYBBP1A, SPIB and TCF20. Interacts with COPS5; indirectly leading to its phosphorylation. Interacts with DSIPI; this interaction inhibits the binding of active AP1 to its target DNA.SUBCELLULAR LOCATION: Nucleus.PTM: Phosphorylation enhances the transcriptional activity. Phosphorylated by PRKDC.SIMILARITY: SwissProt: P05412 ## Belongs to the bZIP family. Jun subfamily. & Contains 1 bZIP domain. View All» Brand Family: Upstate View All» Product Name: Anti-phospho-c-Jun (Thr91) Antibody | 07-568 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 µL View All» Format: Affinity Purified View All» Host: Sheep View All»
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