货号：07-603

品牌：Merck Millipore

规格：EA

目录价：询价

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-p38δ/SAPK4 Antibody | 07-603 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Upstate (Millipore) View All» Specificity: p38δ/SAPK4 View All» Molecular Weight: 42kDa View All» Immunogen: KLH-conjugated, synthetic peptide corresponding to amino acids 353-365 (C-ARKDSRRRSGMKL) of human p38δ/SAPK4 View All» Isotype: IgG View All» Species Reactivity:

• Human

• Rat
  View All» Species Reactivity Note: predicted to cross react with mouse based on sequence homology View All» Quality Assurance: routinely evaluated by immunoblot on RIPA lysates from C6 rat glioma cells View All» Purification Method: Protein A purfied View All» Presentation: 0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30% View All» Storage Conditions: 2 years at -20°C View All» UniProt Number: O15264 View All» Entrez Gene Number: NM_002754 View All» Gene Symbol:
  • MAPK13

  • MGC99536

  • SAPK4

  • PRKM13

  • p38delta
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» Entrez Gene Summary: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is closely related to p38 MAP kinase, both of which can be activated by proinflammatory cytokines and cellular stress. MAP kinase kinases 3, and 6 can phosphorylate and activate this kinase. Transcription factor ATF2, and microtubule dynamics regulator stathmin have been shown to be the substrates of this kinase. View All» UniProt Summary: FUNCTION: SwissProt: O15264 # Responds to activation by environmental stress and pro- inflammatory cytokines by phosphorylating downstream targets. Plays a role in the regulation of protein translation by phosphorylating and inactivating EEF2K.COFACTOR: Magnesium.SIZE: 365 amino acids; 42090 Da TISSUE SPECIFICITY: Expressed in testes, pancreas, small intestine, lung and kidney. Abundant in macrophages, also present in neutrophils, CD4+ T-cells, and endothelial cells.DOMAIN: SwissProt: O15264 The TXY motif contains the threonine and tyrosine residues whose phosphorylation activates the MAP kinases.PTM: Dually phosphorylated on Thr-180 and Tyr-182, which activates the enzyme.SIMILARITY: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily. & Contains 1 protein kinase domain. View All» Brand Family: Upstate View All» Product Name: Anti-p38δ/SAPK4 Antibody | 07-603 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 200 µg View All» Format: Purified View All» Host: Rabbit View All»
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