货号：07-612

品牌：Merck Millipore

规格：50UL

目录价：￥5265.00

市场价格：￥4475.25

会员价格：￥4212.00

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Peroxiredoxin 4 Antibody | 07-612 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Upstate (Millipore) View All» Specificity: Peroxiredoxin 4 View All» Molecular Weight: 21kDa View All» Immunogen: Full-length human Peroxiredoxin 4 recombinant protein tagged with hexahistidine View All» Isotype: IgG View All» Species Reactivity: Human View All» Quality Assurance: routinely evaluated by immunoblot on RIPA lysates from Du145 cells View All» Purification Method: Serum View All» Presentation: antiserum with 0.05% sodium azide before the addition of glycerol to 30% View All» Storage Conditions: 2 years at -20°C View All» UniProt Number: Q13162 View All» Entrez Gene Number: NM_006406 View All» Gene Symbol:

• PRDX4

• Peroxiredoxin-4

• AOE372

• Prx-IV

• AOE37-2
  View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
  • Western Blotting

  • Immunocytochemistry
    View All» Entrez Gene Summary: The protein encoded by this gene is an antioxidant enzyme and belongs to the peroxiredoxin family. The protein is localized to the cytoplasm. Peroxidases of the peroxiredoxin family reduce hydrogen peroxide and alkyl hydroperoxides to water and alcohol with the use of reducing equivalents derived from thiol-containing donor molecules. This protein has been found to play a regulatory role in the activation of the transcription factor NF-kappaB. View All» UniProt Summary: FUNCTION: SwissProt: Q13162 # Probably involved in redox regulation of the cell. Regulates the activation of NF-kappa-B in the cytosol by a modulation of I-kappa-B-alpha phosphorylation.SIZE: 271 amino acids; 30540 Da SUBUNIT: Homodimer or heterodimer with PRDX1; disulfide-linked, upon oxidation (By similarity).SUBCELLULAR LOCATION: Cytoplasm.SIMILARITY: SwissProt: Q13162 ## Belongs to the ahpC/TSA family. MISCELLANEOUS: The active site is the redox-active Cys-124 oxidized to Cys-SOH. Cys-SOH rapidly reacts with Cys-245-SH of the other subunit to form an intermolecular disulfide with a concomitant homodimer formation. The enzyme may be subsequently regenerated by reduction of the disulfide by thioredoxin. & Irreversibly inactivated by overoxidation of Cys- 124 (to Cys-SO(3)H) upon oxidative stress. View All» Brand Family: Upstate View All» Product Name: Anti-Peroxiredoxin 4 Antibody | 07-612 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 50 µL View All» Format: Serum View All» Host: Rabbit View All»
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