货号：07-637

品牌：Merck Millipore

规格：EA

目录价：￥4164.00

市场价格：￥3539.40

会员价格：￥3331.20

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Nova-1 Antibody | 07-637 View All» Replaces: AB5985 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Upstate (Millipore) View All» Specificity: Nova-1 View All» Molecular Weight: 53kDa View All» Immunogen: synthetic peptide corresponding to amino acids 160-172 of mouse Nova-1 View All» Isotype: IgG View All» Species Reactivity:

• Mouse

• Rat
  View All» Quality Assurance: routinely evaluated by immunoblot on mouse spinal cord View All» Purification Method: Immunoaffinity purified View All» Presentation: 0.2M Tris-glycine, pH 7.4, 0.15M NaCl and 0.05% sodium azide before the addition of glycerol to 30%. View All» Storage Conditions: 1 year at -20°C View All» UniProt Number: P51513 View All» Entrez Gene Number: XM_356586 View All» Gene Symbol:
  • NOVA1

  • Nova-1
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» Entrez Gene Summary: This gene encodes a neuron-specific RNA-binding protein, a member of the Nova family of paraneoplastic disease antigens, that is recognized and inhibited by paraneoplastic antibodies. These antibodies are found in the sera of patients with paraneoplastic opsoclonus-ataxia, breast cancer, and small cell lung cancer. Alternatively spliced transcripts encoding distinct isoforms have been described. View All» UniProt Summary: FUNCTION: SwissProt: P51513 # May regulate RNA splicing or metabolism in a specific subset of developing neurons.SIZE: 510 amino acids; 52056 Da SUBUNIT: Interacts with PTBP2 (By similarity).SUBCELLULAR LOCATION: Nucleus.TISSUE SPECIFICITY: Brain.DISEASE: SwissProt: P51513 # Autoantigen in the paraneoplastic opsoclonus myoclonus ataxia (POMA), a paraneoplastic neurological syndrome/disorder (PNS/D) associated with breast cancer, fallopian cancer, and SCLCa and characterized primarily by loss of inhibitory control of motor neurons in the spinal cord and brainstem. Recognized by the IgG autoantibody ANNA-2 (also called anti-Ri).SIMILARITY: SwissProt: P51513 ## Contains 3 KH domains. View All» Brand Family: Upstate View All» Product Name: Anti-Nova-1 Antibody | 07-637 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 µL View All» Format: Affinity Purified View All» Host: Rabbit View All»
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