金山科研平台，产品价格货期咨询微信：jinshanbio Source:Chinese Hamster Ovary cell line, CHO-derived, Arg26-Val342 , with a C-terminal 6-His tag Accession #:AAP35975.1 N-terminal Sequence Analysis:Arg26 Purity:>90%, by SDS-PAGE under reducing conditions and visualized by silver stain. Predicted Molecular Mass:36.8 kDa SDS-PAGE:65-85 kDa, reducing conditions Activity:Measured by the ability of the immobilized protein to enhance the adhesion of T98G human glioblastoma cells to human Fibronectin.When 4 x 10⁴ cells/well are added to plates coated with human Fibronectin (0.1 µg/mL, Catalog # 1918-FN) and rhGPR56 (10 µg/well, 100 µL/well) for 45minutes at 37° C there is a 2 - 4 fold increase in adhesion to human fibronectin induced by the presence of rhGPR56.Optimal dilutions should be determined by each laboratory for each application. Formulation:Lyophilized from a 0.2 µm filtered solution in PBS.See Certificate of Analysis for details. Molecule Information: GPR56 Long Name: G Protein-coupled Receptor 56 Aliases: BFPP; EGF-TM7-like; TM7LN4; TM7XN1 Entrez Gene IDs: 9289 (Human); 14766 (Mouse); 260326 (Rat) Background: GPR56 GPR56 is a widely expressed member of the LN-TM7 family of secretin-like 7-transmembrane (TM) G-protein coupled receptors (GPCR) with long extracellular N-termini. Like other LN-TM7 members, it is an adhesion protein with a highly N-glycosylated extracellular stalk followed by a GPCR proteolytic cleavage site (GPS). Cleavage of the N-terminus from the full-length form is needed for efficient cell surface expression. A human brain developmental disorder, bilateral frontoparietal polymicrogyria, is associated with GPR56 mutations.