货号：07-670

品牌：Merck Millipore

规格：EA

目录价：询价

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-AMPK β Antibody | 07-670 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Upstate (Millipore) View All» Specificity: AMP Activated Protein Kianse Beta 1 (AMPKβ1) View All» Molecular Weight: Mr 40kDa View All» Immunogen: KLH-conjugated, synthetic peptide corresponding to amino acids 256-270 of human AMP Activated Protein Kinase Beta 1 (AMPKβ1) (CRYKKKYVTTLLYKPI) containing a N-terminal cysteine for conjugation purposes. View All» Isotype: IgG View All» Species Reactivity: Mouse View All» Species Reactivity Note: Predicted tocross-react with human, rat, dog, chimpanzee and orangutan based on sequence homology. View All» Quality Assurance: routinely evaluated by immunoblot on mouse liver membrane preparations View All» Purification Method: Immunoaffinity purified View All» Storage Conditions: Stable for 1 year at -20°C from date of shipment View All» UniProt Number: Q9Y478 View All» Entrez Gene Number: NM_006253.4 View All» Gene Symbol:

• PRKAB1

• AMPKb

• AMPK

• MGC17785

• HAMPKb
  View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» Entrez Gene Summary: The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK. This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex. View All» UniProt Summary: FUNCTION: SwissProt: Q9Y478 # AMPK is responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase. Also regulates cholesterol synthesis via phosphorylation and inactivation of hydroxymethylglutaryl-CoA reductase and hormone- sensitive lipase. This is a regulatory subunit, may be a positive regulator of AMPK activity. It may also serve as an adaptor molecule for the catalytic alpha-subunit.SIZE: 270 amino acids; 30382 Da SUBUNIT: Heterotrimer of an alpha catalytic subunit, a beta and a gamma non-catalytic regulatory subunits. Interacts with FNIP1.PTM: Phosphorylated (By similarity).SIMILARITY: SwissProt: Q9Y478 ## Belongs to the 5'-AMP-activated protein kinase beta subunit family. View All» Brand Family: Upstate View All» Product Name: Anti-AMPK β Antibody | 07-670 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 µL View All» Format: Affinity Purified View All» Host: Rabbit View All»
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