货号：07-673

品牌：Merck Millipore

规格：

目录价：￥4516.00

市场价格：￥3838.60

会员价格：￥3612.80

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-dimethyl-Histone H2B (Lys5) Antibody | 07-673 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Upstate (Millipore) View All» Specificity: Recognizes dimethyl-Histone H2B (Lys5), Mr 15 kDa. Does not recognize unmodified Histone H2B. View All» Molecular Weight: 15 kDa View All» Epitope: Dimethyl Lys5 of Histone H2B View All» Immunogen: KLH-conjugated, synthetic peptide containing the sequence (…S [dmK] S…), where [dmK] is dimethyl-lysine 5 of human histone H2B. View All» Modifications: Methylation View All» Isotype: IgG View All» Background Information: Histone methylation is involved in many key epigenetic phenomena, including maintaining the boundaries between heterochromatin and euchromatin. Histone methylation of lysines is generally associated with transcriptional repression, however, some modifications, such as methylation of Lys4 of histone H3, are associated with transcriptional activation. Acetyl Lys5 of histone H2B has been identified in several systems, while the role of methylation of Lys5 of Histone 2B is unknown. View All» Species Reactivity: Human View All» Species Reactivity Note: Reacts with human. Predicted to cross-react with rat and mouse based on sequence homology. View All» Application Notes: Western Blot Analysis: A 1:500-1:1000 dilution detected dimethyl-histone H2B (Lys5) in HeLa acid extracts. Optimal working dilutions must be determined by the end user. View All» Control: Tested on acid extracted proteins from HeLa cells View All» Purification Method: Immunoaffinity purified View All» Presentation: Purified rabbit IgG in buffer containing 0.1 M Tris-glycine, pH 7.4, 0.15 M NaCl, 0.05% sodium azide and 30% glycerol. View All» Storage Conditions: Stable for 1 year at -20°C from date of receipt. Avoid repeated freeze/thaw cycles.Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol-containing solutions to become frozen during storage. View All» UniProt Number: P62807 View All» Entrez Gene Number: NP_778225 View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:

• Western Blotting

• Dot Blot
  View All» Brand Family: Upstate View All» Product Name: Anti-dimethyl-Histone H2B (Lys5) View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 µL View All» Format: Affinity Purified View All» Host: Rabbit View All»
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