货号：07-704

品牌：Merck Millipore

规格：

目录价：￥4247.00

市场价格：￥3609.95

会员价格：￥3397.60

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-EC-SOD Antibody | 07-704 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Upstate (Millipore) View All» Specificity: Rat. Broad species cross-reactivity is expected. View All» Molecular Weight: 45kDa View All» Immunogen: KLH-conjugated, synthetic peptide corresponding to the sequence 227-236 (ERKKRRRESE-C) which corresponds to human EC-SOD (extracellular superoxide dismutase or SOD3) with a c-terminal cysteine added for conjugation purposes. The immunizing sequence is identical in mouse, rat, chimpanzee, chicken, cow, dog, rabbit, and yeast. View All» Isotype: IgG View All» Species Reactivity: Rat View All» Species Reactivity Note: Broad species cross-reactivity is expected. View All» Quality Assurance: Routinely evaluated by immunoblot. View All» Purification Method: Protein A purfied View All» Storage Conditions: 2 years at -20°C from date of shipment View All» UniProt Number: P08294 View All» Entrez Gene Number: NM_003102.2 View All» Gene Symbol:

• SOD3

• MGC20077

• Cu-Znprecursor

• EC-SOD
  View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» Entrez Gene Summary: This gene encodes a member of the superoxide dismutase (SOD) protein family. SODs are antioxidant enzymes that catalyze the dismutation of two superoxide radicals into hydrogen peroxide and oxygen. The product of this gene is thought to protect the brain, lungs, and other tissues from oxidative stress. The protein is secreted into the extracellular space and forms a glycosylated homotetramer that is anchored to the extracellular matrix (ECM) and cell surfaces through an interaction with heparan sulfate proteoglycan and collagen. A fraction of the protein is cleaved near the C-terminus before secretion to generate circulating tetramers that do not interact with the ECM. View All» UniProt Summary: FUNCTION: SwissProt: P08294 # Destroys radicals which are normally produced within the cells and which are toxic to biological systems.COFACTOR: Binds 1 copper ion per subunit (By similarity). & Binds 1 zinc ion per subunit (By similarity).SIZE: 240 amino acids; 25851 Da SUBUNIT: Homotetramer.SUBCELLULAR LOCATION: Secreted, extracellular space. Note=99% of EC-SOD is anchored to heparan sulfate proteoglycans in the tissue interstitium, and 1% is located in the vasculature in equilibrium between the plasma and the endothelium.TISSUE SPECIFICITY: Major SOD isoenzyme in extracellular fluids such as plasma, lymph and synovial fluid.SIMILARITY: SwissProt: P08294 ## Belongs to the Cu-Zn superoxide dismutase family. View All» Brand Family: Upstate View All» Product Name: Anti-EC-SOD Antibody | 07-704 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 200 µg View All» Format: Purified View All» Host: Rabbit View All»
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