货号：07-723

品牌：Merck Millipore

规格：

目录价：￥3908.00

市场价格：￥3321.80

会员价格：￥3126.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Apobec3 Antibody, NT | 07-723 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Upstate (Millipore) View All» Specificity: Apobec3 View All» Molecular Weight: 51kDa. An additional protein was also detected, Mr 31kDa. View All» Immunogen: KLH-conjugated, synthetic peptide corresponding to amino acids 82-95 (C-DKVLKVLSPREEFK) of mouse apolipoprotein B editing complex 3 (Apobec3), with an N-terminal cysteine added for conjugation purposes. View All» Isotype: IgG View All» Species Reactivity: Mouse View All» Quality Assurance: Routinely evaluated by immunoblot. View All» Purification Method: Immunoaffinity purified View All» Presentation: Affinity purified antibody in 0.1M Tris-Glycine, 0.15M NaCl, 0.05% Sodium Azide, pH 7.4. View All» Storage Conditions: Maintain for 1 year at 2 to 8°C from date of shipment. View All» UniProt Number: Q8IUX4 View All» Entrez Gene Number:

• NM_001006666.1

• NM_145298.5
  View All» Gene Symbol:
  • APOBEC3F

  • MGC74891

  • KA6

  • BK150C2.4.MRNA

  • ARP8
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» Entrez Gene Summary: This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been identified. View All» UniProt Summary: FUNCTION: SwissProt: Q8IUX4 # After being packaged into HIV-1 virions, blocks productive infection by massively editing dC residues to dU on the DNA minus strand during reverse transcription. The editing of the minus strand DNA of HIV-1 during reverse transcription leads to G- to-A transitions in the plus strand. The inhibition of viral replication is either due to the degradation of the minus strand before its integration or to the lethality of the hypermutations.COFACTOR: Zinc (By similarity).SIZE: 373 amino acids; 45020 Da SUBUNIT: Forms heterodimers with APOBEC3G. Binds HIV-1 Vif. In the absence of Vif protein, specifically packaged into HIV-1 virions.TISSUE SPECIFICITY: Widely expressed, including in lymphoid tissues, such as thymus and peripheral blood leukocytes. No expression detected in permissive lymphoid.SIMILARITY: SwissProt: Q8IUX4 ## Belongs to the cytidine and deoxycytidylate deaminase family. MISCELLANEOUS: It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. View All» Brand Family: Upstate View All» Product Name: Anti-Apobec3 Antibody, NT | 07-723 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 µL View All» Format: Affinity Purified View All» Host: Rabbit View All»
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