金山科研平台，产品价格货期咨询微信：jinshanbio Source:Mouse myeloma cell line, NS0-derived, Asp25-Val339, with a C-terminal 6-His tag Accession #:ABA18645 N-terminal Sequence Analysis:Asp25 Purity:>90%, by SDS-PAGE under reducing conditions and visualized by silver stain. Predicted Molecular Mass:34.6 kDa SDS-PAGE:40-44 kDa, reducing conditions Activity:Measured by its ability to bind biotinylated advanced glycation endproducts of bovine serum albumin (AGE-BSA, R&D Systems, Catalog # BT4127). Formulation:Lyophilized from a 0.2 µm filtered solution in PBS.See Certificate of Analysis for details. Molecule Information: RAGE Long Name: Receptor for Advanced Glycation End Products Aliases: AGER Entrez Gene IDs: 177 (Human); 11596 (Mouse); 81722 (Rat) Background: RAGE View RAGE IHC images. RAGE (receptor for advanced glycation end products) is a multi-ligand type I transmembrane glycoprotein belonging to the immunoglobulin (Ig) superfamily. RAGE ligands include advanced glycation end products (AGEs), amyloid-beta (A beta) peptide, HMG-1 (also known as Amphoterin), and several members of the S100 protein superfamily. RAGE has potential involvement in several pathological processes including diabetes, Alzheimer's disease (AD), systemic amyloidosis, and tumor growth. RAGE may also mediate several physiological functions such as neuronal outgrowth, survival, and regeneration, and play a part in pro-inflammatory reactions.