金山科研平台，产品价格货期咨询微信：jinshanbio Source:E. coli-derived, Pro96-Val195 Accession #:P97463.1 N-terminal Sequence Analysis:Pro96 Structure:Disulfide-linked homodimer Purity:>95%, by SDS-PAGE under reducing conditions and visualized by silver stain. Predicted Molecular Mass:11.7 kDa (monomer) Activity:Measured by its binding ability in a functional ELISA.Immobilized Recombinant Mouse GFR alpha ‑2/GDNFR alpha ‑2 Fc Chimera (Catalog# 429-FR) at1µg/mL can bind Recombinant Mouse Neurturin with an apparent K_D <3.0 nM.Measured by its ability to support the survival and stimulate neurite outgrowth of dissociated chick embryonic dorsal root ganglia (DRG) neurons. Davies,A.M. (1989) in Neurotrophic Factor Bioassay Using Dissociated Neurons, Nerve Growth Factor. Rush,R.A. (eds): John Willey and Sons, Ltd. 95.

The ED₅₀ for this effect is typically 2-10 ng/mL.

Also measured in a cell proliferation assay using SH-SY5Y human neuroblastoma cells.