金山科研平台，产品价格货期咨询微信：jinshanbio Source:E. coli-derived, Gln24-Arg96 Accession #:Q5SVU3 N-terminal Sequence Analysis:Gln24 Purity:>97%, by SDS-PAGE under reducing conditions and visualized by silver stain. Predicted Molecular Mass:8.5 kDa Activity:Measured by its ability to chemoattract BaF3 mouse pro‑B cells transfected with human CCR2A.The ED₅₀ for this effect is typically2-10ng/mL.Measured by its ability to chemoattract 2-day cultured human monocytes. Matsushima,K. etal. (1989) J.Exp. Med. 169:1485.The ED₅₀ for this effect is typically 5-20 ng/mL. Molecule Information: CCL2/JE/MCP-1 Aliases: MCAF; MCP-1 Entrez Gene IDs: 6347 (Human); 20296 (Mouse); 24770 (Rat); 403981 (Canine) Background: CCL2/MCP-1/JE View CCL2 IHC images. MCP-1, also known as monocyte chemotactic and activating factor (MCAF), was initially purified based on its ability to chemoattract monocytes. Subsequent to its cloning and sequencing, it became evident that this protein is also identical to the product of the human JE gene. The JE gene, originally identified in mouse fibroblasts, is a platelet-derived growth factor (PDGF)-inducible gene.