货号：07-835

品牌：Merck Millipore

规格：

目录价：￥4469.00

市场价格：￥3798.65

会员价格：￥3575.20

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-phospho-GSK-3β (Ser9) View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Upstate (Millipore) View All» Specificity: Recognizes phospho-GSK-3β (Ser9). View All» Molecular Weight: 47 kDa View All» Immunogen: Peptide corresponding to amino acid region encompassing the human and rat phospho-GSK-3β (Ser9). View All» Modifications: Phosphorylation View All» Isotype: IgG View All» Species Reactivity:

• Human

• Rat
  View All» Quality Assurance: Routinely evaluated by immunoblot. View All» Purification Method: Immunoaffinity purified View All» Storage Conditions: 2 years at -20°C View All» UniProt Number: P49841 View All» Entrez Gene Number: NM_002093.2 View All» Gene Symbol: GSK3B View All» Alternate Names: GSK3B , Glycogen Synthase Kinase 3 beta View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» Entrez Gene Summary: Glycogen synthase kinase-3 (GSK3) is a proline-directed serine-threonine kinase that was initially identified as a phosphorylating and inactivating glycogen synthase. Two isoforms, alpha (GSK3A; MIM 606784) and beta, show a high degree of amino acid homology (Stambolic and Woodgett, 1994 [PubMed 7980435]). GSK3B is involved in energy metabolism, neuronal cell development, and body pattern formation (Plyte et al., 1992 [PubMed 1333807]).[supplied by OMIM] View All» UniProt Summary: FUNCTION: SwissProt: P49841 # Participates in the Wnt signaling pathway. Implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN. Phosphorylates JUN at sites proximal to its DNA-binding domain, thereby reducing its affinity for DNA.SIZE: 420 amino acids; 46744 Da SUBUNIT: Monomer (By similarity). Interacts with NIN and CABYR.TISSUE SPECIFICITY: Expressed in testis, thymus, prostate and ovary and weakly expressed in lung, brain and kidney.PTM: Phosphorylated by AKT1 and ILK1.SIMILARITY: SwissProt: P49841 ## Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily. & Contains 1 protein kinase domain. View All» Brand Family: Upstate View All» Product Name: Anti-phospho-GSK-3β (Ser9) View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 µL View All» Format: Affinity Purified View All» Host: Rabbit View All»
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