R&D Systems代理4880-AN-050 Recombinant Mouse Angiopoietin-like 4 Protein, CF (50 UG)

2025-06-27

货号:4880-AN-050

品牌:R&D Systems

规格:50ug

目录价:¥4900.00

市场价格:¥3920.00

会员价格:¥3920.00

  • 到货时间:3~4周

    金山科研平台,产品价格货期咨询微信:jinshanbio Source:Chinese Hamster Ovary cell line, CHO-derived, Gln24-Ser410, with a C-terminal 6-His tag Accession #:Q9Z1P8 N-terminal Sequence Analysis:No results obtained: Gln24 predicted Structure:Oligomer Purity:>95%, by SDS-PAGE under reducing conditions and visualized by silver stain. Endotoxin Level: Predicted Molecular Mass:44.2 kDa SDS-PAGE:55-65 kDa, reducing conditions Activity:Measured by its ability to inhibit lipoprotein lipase activity. Yoshida, K. et al. (2002) J. Lipid Res. 43:1770.The IC50 value under conditions in which lipoprotein lipase is present at 5 units/mL, and p-nitrophenyl butyrate concentration is 1mM in 0.1M sodium phosphate, 0.15 M NaCl, 0.5% Triton® X-100, pH 7.2, is approximately0.1 -1 µg/mL. Formulation:Lyophilized from a 0.2 µm filtered solution in PBS and NaCl.See Certificate of Analysis for details. Molecule Information: Angiopoietin-like Protein 4/ANGPTL4 Aliases: ANGPTL4; FIAF; HFARP; PGAR Entrez Gene IDs: 51129 (Human); 57875 (Mouse); 362850 (Rat) Background: Angiopoietin-like 4 Angiopoietin-like 4 (ANGPTL4) is a liver secreted glycoprotein that is structurally related to the angiopoietins, although it does not bind Tie-1 or Tie-2. Full length ANGPTL4 circulates in the plasma as do its proteolytically cleaved coiled coil and fibrinogen-like domains. ANGPTL4 promotes an increase in circulating triglyceride levels by directly inhibiting lipoprotein lipase. ANGPTL4 expression is induced by fasting and hypoxia but suppressed in type 2 diabetes.

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