金山科研平台，产品价格货期咨询微信：jinshanbio Source:Chinese Hamster Ovary cell line, CHO-derived, Ile21-Arg971, with a C-terminal 6-His tag Accession #:P20023 N-terminal Sequence Analysis:Ile21 Purity:>95%, by SDS-PAGE under reducing conditions and visualized by silver stain. Predicted Molecular Mass:105 kDa SDS-PAGE:130-140 kDa, reducing conditions Activity:Measured by its binding ability in a functional ELISA.When CD21 is coated at 5 µg/mL, complement component iC3b binds with apparent K_D < 10 nM. Formulation:Lyophilized from a 0.2 µm filtered solution in PBS.See Certificate of Analysis for details. Molecule Information: CD21 Aliases: C3DR; CD21; CR2 Entrez Gene IDs: 1380 (Human); 12902 (Mouse); 289395 (Rat) Background: CD21 CD21, also known as complement receptor 2 (CR2), is a 145 kDa transmembrane protein that contains 15 tandem SCR/SUSHI repeats. CD21 is primarily expressed on B cells, follicular dendritic cells, and T cells. It binds the complement component fragments iC3b, C3d, and C3d,g and forms complexes with CD19 and CD35. CD21 is required for germinal center development, antibody production, and B cell tolerance. It also functions as a cellular uptake receptor for Epstein-Barr virus.