金山科研平台，产品价格货期咨询微信：jinshanbio Source:Chinese Hamster Ovary cell line, CHO-derived, Ser17-Pro220, with a C-terminal 6-His tag Accession #:Q9Y5C1 N-terminal Sequence Analysis:Ser17 Structure:Oligomer Purity:>95%, by SDS-PAGE under reducing conditions and visualized by silver stain. Endotoxin Level: Predicted Molecular Mass:24.6 kDa SDS-PAGE:35-43 kDa, reducing conditions Activity:Measured by its ability to inhibit lipoprotein lipase activity. Yoshida, K. et al. (2002) J. Lipid Res. 43:1770.The IC₅₀ value under conditions in which lipoprotein lipase is present at 5 units/mL, and p-nitrophenyl butyrate concentration is 1mM in 0.1Msodium phosphate, 0.15 M NaCl, 0.5% Triton^® X-100, pH 7.2, is approximately2 - 8 µg/mL. Formulation:Lyophilized from a 0.2 µm filtered solution in PBS and NaCl.See Certificate of Analysis for details. Molecule Information: Angiopoietin-like Protein 3/ANGPTL3 Aliases: AGNPT5; Ang-5; Angiopoietin-5; ANGPTL3 Entrez Gene IDs: 27329 (Human); 30924 (Mouse) Background: Angiopoietin-like 3 Angiopoietin-like 3 (ANGPTL3) is a liver secreted glycoprotein that is structurally related to the angiopoietins, although it does not bind Tie-1 or Tie-2. Full length ANGPTL3 circulates in the plasma as do its proteolytically cleaved coiled coil and fibrinogen-like domains. ANGPTL3 promotes an increase in circulating triglyceride levels by directly inhibiting lipoprotein lipase. ANGPTL3 expression is dysregulated in some strains of obese and diabetic mice.