货号：09-076

品牌：Merck Millipore

规格：

目录价：￥3639.00

市场价格：￥3093.15

会员价格：￥2911.20

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-GATA3 Antibody | 09-076 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Upstate (Millipore) View All» Specificity: Recognizes GATA3 View All» Molecular Weight: 48 kda View All» Epitope: a.a. 3-17 View All» Immunogen: KLH conjugated synthetic peptide (VTADQPRWVSHHHPA(C) corresponding to a.a. 3-17 of human GATA3 View All» Isotype: IgG View All» Background Information: GATA3 is a transcription factor containing a zinc finger domain. GATA3 is primarily expressed in T cells, where it thought to participate in T-cell receptor gene activation through binding to enhancers. Analysis of conditional Gata3 knockout mice confirmed the critical role of GATA-3 in helper T cell differentiation and proliferation. Cells expressing GATA-3 develop the profile of Th2 cells, secreting IL-4, IL-5 and IL-13. Binding of GATA-3 in the regulatory regions of the genes of these cytokines alters chromatin structure, increasing accessibility to other transcription factors. T cell receptor activation activates NFAT and other transcription factors that cooperate with GATA-3 in inducing Th2 cell differentiation. Blocking GATA-3 action has been suggested as a therapeutic strategy to treat asthma. GATA-3 has also been implicated in developmental processes such as the development of the inner ear. View All» Species Reactivity:

• Human

• Rat
  View All» Quality Assurance: Routinely evaluated by immunoblot. View All» Purification Method: Immunoaffinity purified View All» Presentation: Immunoaffinity purified rabbit IgG in PBS, 0.1% sodium azide. View All» Storage Conditions: Stable for 1 year at -20°C from date of receipt.Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. View All» UniProt Number: P23771 View All» Entrez Gene Number: 2625 View All» Gene Symbol:
  • HDR

  • MGC2346

  • MGC5199

  • MGC5445
    View All» Alternate Names: GATA binding protein 3GATA-binding factor 3 HDR 2Trans-acting T-cell-specific transcription factor GATA-3 MGC2346 MGC5199 MGC5445 View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» UniProt Summary: Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'. Genatlas biochemistry entry for GATA3:T cell specific transcription factor,GATA sequence binding protein in T cell receptor, also expressed in endothelial cell, placenta, transcriptional regulator in kidney, adrenal gland, embryonic brain, adult nervous system endocardium, associated with a special class of nuclear bodies. View All» Brand Family: Upstate View All» Product Name: Anti-GATA3 Antibody (09-076) View All» Concentration: 1 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Affinity Purified View All» Host: Rabbit View All»
    © 金山科研平台是专业的授权总代理区域代理经销平台。
    © 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
    © 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
    © 本文地址：https://www.16ao.com/thread-136599.htm
    © Merck Millipore代理09-076 Anti-GATA3 (rabbit polyclonal)，产品报价联系微信jinshanbio