货号：09-091

品牌：Merck Millipore

规格：EA

目录价：￥3468.00

市场价格：￥2947.80

会员价格：￥2774.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-MCM3 Antibody | 09-091 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: This antibody recognizes MCM3. View All» Molecular Weight: Approximately 100-110 kDa View All» Immunogen: KLH-conjugated linear peptide corresponding to amino acids 692-708 of MCM3. View All» Background Information: MCM3 (minichromosome maintenance complex component 3) is part of the hexameric MCM DNA helicase, a complex replicative helicase, which plays essential roles in DNA replication. View All» Species Reactivity:

• Human

• Horse

• Canine
  View All» Species Reactivity Note: Proven to react with Human. Predicted to react with Dog and Horse based on sequence homology. View All» Control: Jurkat cell lysate View All» Quality Assurance: Evaluated by Western Blot on Jurkat cell lysate.Western Blot Analysis: A 1:4,000 dilution of this antibody was used to detect MCM3 on Jurkat cell lysate. View All» Purification Method: Affinity Purfied View All» Presentation: Purified rabbit serum in 0.1M Tris-Glycine (pH7.4), 150mM NaCl containing 0.05% sodium azide. View All» Storage Conditions: Maintain refrigerated at 2-8°C for 1 year from date of receipt. View All» UniProt Number: P25205 View All» Entrez Gene Number: NP_002379 View All» Gene Symbol:
  • HCC5

  • MGC1157

  • OTTHUMP00000016600

  • P1-MCM3

  • P1.h

  • RLFB
    View All» Alternate Names:
    • DNA polymerase alpha holoenzyme-associated protein P1

    • DNA replication factor MCM3

    • MCM3 minichromosome maintenance deficient 3

    • MCM3 minichromosome maintenance deficient 3 (S. cerevisiae)

    • P102 protein

    • RLF subunit beta

    • cervical cancer proto-oncogene 5

    • hRlf beta subunit

    • minichromosome maintenance complex component 3

    • minichromosome maintenance deficient (S. cerevisiae) 3

    • minichromosome maintenance deficient 3

    • replication licensing factor, beta subunit
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» Entrez Gene Summary: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with, and thus is acetlyated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. View All» UniProt Summary: FUNCTION: Acts as a factor that allows the DNA to undergo a single round of replication per cell cycle. Required for DNA replication and cell proliferation.SUBCELLULAR LOCATION: Nucleus. PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. MISCELLANEOUS: Associated with the replication-specific DNA polymerase alpha.SEQUENCE SIMILARITIES: Belongs to the MCM family.Contains 1 MCM domain. View All» Product Name: Anti-MCM3 View All» Concentration: 1 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 µg View All» Format: Affinity Purified View All» Host: Rabbit View All»
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