货号：09-129

品牌：Merck Millipore

规格：100UL

目录价：￥5053.00

市场价格：￥4295.05

会员价格：￥4042.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-SFRP4 Antibody | 09-129 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Upstate (Millipore) View All» Specificity: Recognizes SFRP4 View All» Molecular Weight: 55 kDa View All» Immunogen: Recombinant full length human GST-tagged SFRP4 protein. View All» Isotype: IgG View All» Species Reactivity: Human View All» Application Notes: Immunoblot: 1:500-1:5000 dilution is recommended depending on cell type and method of stimulation. Optimal working dilutions must be determined by end user. View All» Quality Assurance: Routinely evaluated by immunoblot. View All» Purification Method: Serum View All» UniProt Number: Q6FHJ7 View All» Entrez Gene Number: NM_003014.2 View All» Gene Symbol:

• SFRP4

• sFRP-4

• FRPHE

• frpHE

• MGC26498

• FRP-4

• FrpHE
  View All» Alternate Names: secreted frizzled-related protein 4, FRP-4, sFRP-4, FRPHE View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» Entrez Gene Summary: Secreted frizzled-related protein 4 (SFRP4) is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. The expression of SFRP4 in ventricular myocardium correlates with apoptosis related gene expression. View All» UniProt Summary: FUNCTION: SwissProt: Q6FHJ7 # Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP4 may act as a regulator of adult uterine morphology and function. Increases apoptosis during ovulation possibly through modulation of FZ1/FZ4/WNT4 signaling (By similarity). Has phosphaturic effects by specifically inhibiting sodium-dependent phosphate uptake.SIZE: 346 amino acids; 39827 Da SUBCELLULAR LOCATION: Secreted.TISSUE SPECIFICITY: Expressed in mesenchymal cells. Highly expressed in the stroma of proliferative endometrium. Expressed in cardiomyocytes.DOMAIN:SwissProt: Q6FHJ7 The FZ domain is involved in binding with Wnt ligands (By similarity).DISEASE:SwissProt: Q6FHJ7 # Associated with tumor-induced osteomalacia, a disorder in which there is an increase in renal phosphate excretion and a reduction in serum phosphate levels leading to hyperphosphaturia, hypophosphatemia and rickets.SIMILARITY: Belongs to the secreted frizzled-related protein (sFRP) family. & Contains 1 FZ (frizzled) domain. & Contains 1 NTR domain. View All» Brand Family: Upstate View All» Product Name: Anti-SFRP4 Antibody | 09-129 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 µL View All» Format: Serum View All» Host: Rabbit View All»
  © 金山科研平台是专业的授权总代理区域代理经销平台。
  © 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
  © 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
  © 本文地址：https://www.16ao.com/thread-136642.htm
  © Merck Millipore代理09-129 Anti-SFRP4 Antibody;store at -20℃，产品报价联系微信jinshanbio