货号：09-142

品牌：Merck Millipore

规格：100UL

目录价：￥6895.00

市场价格：￥5860.75

会员价格：￥5516.00

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-phospho-ACK1 (Tyr284) Antibody | 09-142 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Upstate (Millipore) View All» Specificity: Recognizes ACK1 phosphorylated on Tyrosine residue 284. View All» Molecular Weight: 114 kDa View All» Immunogen: KLH conjugated synthetic peptide corresponding to amino acids surrounding Tyr 284 of human ACK1. View All» Modifications: Phosphorylation View All» Isotype: IgG View All» Species Reactivity: Human View All» Control: Brain tissue View All» Quality Assurance: Routinely evaluated by immunoblot. View All» Purification Method: Immunoaffinity purified View All» Presentation: Immunoaffinity Purified rabbit polyclonal IgG in 0.02M PBS, 0.25M sodium chloride (pH 7.6) containing 0.1% sodium azide and 30% glycerol. View All» Storage Conditions: Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. View All» UniProt Number: Q07912 View All» Entrez Gene Number:

• NM_001010938.1

• NM_005781.4
  View All» Gene Symbol:
  • TNK2

  • p21cdc42Hs

  • ACK1

  • ACK-1

  • FLJ45547

  • FLJ44758

  • ACK
    View All» Alternate Names: TNK2, tyrosine kinase non-receptor 2, p21cdc42Hs, activated Cdc42-associated kinase 1, activated p21cdc42Hs kinase View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» Entrez Gene Summary: This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined. View All» UniProt Summary: FUNCTION: SwissProt: Q07912 # Downstream effector of CDC42 which mediates CDC42- dependent cell migration via phosphorylation of BCAR1. Binds to both poly- and mono-ubiquitin and regulates ligand-induced degradation of EGFR. Participates in clathrin-mediated endocytosis. May be involved both in adult synaptic function and plasticity and in brain development.COFACTOR: Magnesium.SIZE: 1036 amino acids; 114327 Da SUBUNIT: Interacts with CDC42. Interacts with activated CSPG4.SUBCELLULAR LOCATION: Cell membrane (By similarity).SIMILARITY: SwissProt: Q07912 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. & Contains 1 CRIB domain. & Contains 1 protein kinase domain. & Contains 1 SH3 domain. View All» Brand Family: Upstate View All» Product Name: Anti-phospho-ACK1 (Tyr284) Antibody | 09-142 View All» Concentration: 0.5 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μL View All» Target / Localization: Clathrin-mediated endocytosis View All» Format: Affinity Purified View All» Host: Rabbit View All»
    © 金山科研平台是专业的授权总代理区域代理经销平台。
    © 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
    © 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
    © 本文地址：https://www.16ao.com/thread-136646.htm
    © Merck Millipore代理09-142 Anti-phospho-ACK1 (Tyr284) Antibody;store at -20℃，产品报价联系微信jinshanbio