金山科研平台，产品价格货期咨询微信：jinshanbio Source:Mouse myeloma cell line, NS0-derived, Gln25-Leu187, with a C-terminal 10-His tag Accession #:Q49AH0 N-terminal Sequence Analysis:No results obtained: Gln25 predicted Purity:>95%, by SDS-PAGE under reducing conditions and visualized by silver stain. Predicted Molecular Mass:19.9 kDa SDS-PAGE:19-25 kDa, reducing conditions Activity:Measured by its ability to enhance neurite outgrowth of E16-E18 rat embryonic cortical neurons.Able to significantly enhance neurite outgrowth when immobilized at 6 - 24 µg/mL on a nitrocellulose-coated microplate. Formulation:Lyophilized from a 0.2 µm filtered solution in PBS.See Certificate of Analysis for details. Molecule Information: CDNF Long Name: Conserved Dopamine Neurotrophic Factor Aliases: ARMETL1 Entrez Gene IDs: 441549 (Human); 227526 (Mouse); 361276 (Rat) Background: CDNF View CDNF IHC images. CDNF (conserved dopamine neurotrophic factor), also called Armetl1 (arginine-rich, mutated in early stage tumors-like 1) in mouse, is a secreted protein that shares 62% amino acid identity with human MANF (mesencephalic-astrocyte-derived neurotrophic factor), also called Armet in mouse. Like MANF and GDNF (glial cell-derived neurotrophic factor), CDNF promotes survival of dopaminergic neurons in vitro. In a rat Parkinson's disease model, CDNF also promotes rescue and restoration of dopaminergic neurons in vivo.