货号：09-267

品牌：Merck Millipore

规格：

目录价：￥4146.00

市场价格：￥3524.10

会员价格：￥3316.80

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-human Tks4 Antibody | 09-267 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: The antibody recognizes human Tks4. View All» Molecular Weight: ~ 130 kDa View All» Epitope: a. a. 431-595 View All» Immunogen: Recombinant protein containing amino acids 431-595 of human Tks4. View All» Background Information: Tks4 (gene symbol SH3PXD2B) is a novel adaptor protein; also known as SH3 and PX domain-containing protein 2B, (Courtneidge, 2005). It is closely related to Tks5 (gene symbol SH3PXD2A) and like Tks5, appears to play a role in the formation and function of podosome/invadopodia based on studies of Src-transformed fibroblasts (Buschman, 2009). Additionally, Tks4 may be involved in the recruitment of MT1-MMP and ECM degradation.Tks4 is broadly expressed and localizes in the cytoplasm of the podosome. View All» Species Reactivity:

• Human

• Mouse
  View All» Species Reactivity Note: Human and mouse (76% homology). Predicted to cross react with rat (77% homology). Reactivity with other species has not been tested. View All» Control: NIH3T3 cell lysate. View All» Quality Assurance: Evaluated on a representative lot by Immunoprecipitation followed by Western blot on NIH3T3 cell lysate using Anti-human Tks4. View All» Purification Method: Protein A purfied View All» Presentation: Purified in 0.1M Tris-Glycine, pH 7.4, 150 mM NaCl with 0.05% NaN3. View All» Storage Conditions: Maintain at 2-8°C for up to 1 year from date of receipt. View All» UniProt Number: A1X283 View All» Entrez Gene Number: A1X283 View All» Gene Symbol:
  • FAD49

  • FLJ20831

  • HOFI

  • KIAA1295
    View All» Alternate Names:
    • Adapter protein HOFI

    • Factor for adipocyte differentiation 49

    • SH3 and PX domains 2B

    • adaptor protein HOFI
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
      • Western Blotting

      • Immunoprecipitation
        View All» UniProt Summary: FUNCTION: Binds a range of phosphoinositides including phosphatidylinositol 3,5-biphosphate and, to a lesser extent, phosphatidylinositol 3-phosphate, phosphatidylinositol 4-phosphate and phosphatidylinositol 5-biphosphate. Plays a role in mitotic clonal expansion during the immediate early stage of adipocyte differentiation By similarity.SUBCELLULAR LOCATION: Cytoplasm By similarity. DOMAIN: The PX domain is required for binding phosphoinositides and can also bind to the third SH3 domain By similarity.SEQUENCE SIMILARITIES: Belongs to the SH3PXD2 family.Contains 1 PX (phox homology) domain.Contains 4 SH3 domains. View All» Product Name: Anti-human Tks4 View All» Concentration: 1 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 µg View All» Format: Purified View All» Host: Rabbit View All»
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