货号：09-283

品牌：Merck Millipore

规格：EA

目录价：询价

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-19S regulator non-ATPase subunit S12/Rpn8 Antibody | 09-283 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Upstate (Millipore) View All» Specificity: Recognizes 19S regulator non-ATPase subunit S12/Rpn8. View All» Molecular Weight: 37 kDa View All» Immunogen: Recombinant protein corresponding to residues 1-205 of human Rpn8. View All» Isotype: Ig View All» Species Reactivity: Human View All» Presentation: 100 µL of immunoglobulin in PBS containing 0.01 M sodium azide. Dilute to working strength with phosphate buffered saline pH 7.2-7.4. View All» Storage Conditions: Stable for 1 year at -20°C from date of shipment for up to 12 months. View All» UniProt Number: P51665 View All» Entrez Gene Number: NM_002811.3 View All» Gene Symbol:

• PSMD7

• S12

• P40

• MOV34

• MOV34L
  View All» Alternate Names: 26S proteasome non-ATPase subunit 7; S12 View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» Entrez Gene Summary: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 17. View All» UniProt Summary: FUNCTION: SwissProt: P51665 # Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.SIZE: 324 amino acids; 37025 Da SIMILARITY: SwissProt: P51665 ## Belongs to the peptidase M67A family. & Contains 1 MPN (JAB/Mov34) domain. View All» Brand Family: Upstate View All» Product Name: Anti-19S regulator non-ATPase subunit S12/Rpn8 Antibody | 09-283 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 µL View All» Format: Purified View All» Host: Sheep View All»
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