货号：09-718

品牌：Merck Millipore

规格：100Ug

目录价：￥5053.00

市场价格：￥4295.05

会员价格：￥4042.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-TGIF2 Antibody | 09-718 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Upstate (Millipore) View All» Specificity: Recognizes TGIF2 View All» Molecular Weight: 28 kDa View All» Epitope: a.a. 189-203 View All» Immunogen: KLH conjugated synthetic peptide (C)-EQDKEDFSSFQLLVE corresponding to a.a. 189-203 of human TGIF. View All» Background Information: TGIF2 (TGFbeta-induced transcription factor 2) is a homeobox protein that represses transcription by directly binding the DNA sequence 5'-CTGTCAA-3' or by interacting with the transcriptional modulator SMAD3. TGIF2 also is thought to repress transcription via the recruitment of histone deacetylase proteins. TGIF2 is phosphorylated in response to EGF signaling by the Ras/MAPK pathway. TGIF2 is amplified and overexpressed in several ovarian cancer cell lines. View All» Species Reactivity:

• Human

• Mouse

• Rat
  View All» Quality Assurance: Routinely evaluated by immunoblot. View All» Purification Method: Immunoaffinity purified View All» Presentation: Immunoaffinity purified rabbit IgG in PBS, 0.1% sodium azide, 30% glycerol View All» Storage Conditions: Stable for 1 year at -20°C from date of receipt.Handling Recommendations: Prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. View All» UniProt Number: Q9GZN2 View All» Entrez Gene Number: 60436 View All» Alternate Names:
  • TGFB-induced factor homeobox 2

  • transcription growth factor-beta-induced factor 2
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» Entrez Gene Summary: The protein encoded by this gene is a DNA-binding homeobox protein and a transcriptional repressor.The encoded protein appears to repress transcription by recruiting histone deacetylases to TGFbeta-responsive genes. This gene is amplified and overexpressed in some ovarian cancers, and mutations in this gene can cause holoprosencephaly. View All» UniProt Summary: Transcription factor that controls the expression of the TH1 cytokine, interferon-gamma. Initiates TH1 lineage development from naive TH precursor cells both by activating TH1 genetic programs and by repressing the opposing TH2 programs. View All» Brand Family: Upstate View All» Product Name: Anti-TGIF2 Antibody | 09-718 View All» Concentration: 0.5 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Affinity Purified View All» Host: Rabbit View All»
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