金山科研平台，产品价格货期咨询微信：jinshanbio Source:Mouse myeloma cell line, NS0-derived Accession #:Q544A9 N-terminal Sequence Analysis:Ile26 Structure:Disulfide-linked homodimer Purity:>90%, by SDS-PAGE under reducing conditions and visualized by silver stain. Predicted Molecular Mass:51 kDa SDS-PAGE:65-85 kDa, reducing conditions Activity:Measured by its ability to inhibit the IL-4-dependent proliferation of HT‑2 mouse Tcells. Tsang,M. etal. (1995) Cytokine 7:389.The ED₅₀ for this effect is typically 0.05-0.2µg/mL in the presence of 3ng/mL of recombinant mouse IL-4. Formulation:Lyophilized from a 0.2 µm filtered solution in PBS.See Certificate of Analysis for details. Molecule Information: IL-4 R alpha Long Name: Interleukin 4 Receptor alpha Aliases: CD124; IL4R Entrez Gene IDs: 3566 (Human); 16190 (Mouse) Background: IL-4 Receptor Two types of IL-4 receptor complexes have been described. The typeI IL-4 receptor complex is composed of a high-affinity IL-4-binding subunit (referred to as IL-4 R or IL-4 R alpha) and the common gamma chain that does not bind IL-4 by itself. The type II IL-4 receptor complex is composed of IL-4 R and IL-13 R alpha 1. Besides IL-4 signals, the type II IL-4 receptor complex can also transduce IL-13 signals. In the type II complex, IL-4 R subunit binds only IL-4 and not IL-13. Similarly, the IL-13 R alpha 1 subunit binds only IL-13 and not IL-4.