货号:09-836
品牌:Merck Millipore
规格:EA
目录价:¥4410.00
市场价格:¥3748.50
会员价格:¥3528.00
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Description:
Anti-phospho-Histone H1.B (Ser27) Antibody | 09-836
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Promotional Text:
Special Shipping Offer on Antibodies100% Performance Guaranteed
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Specificity:
This antibody recognizes phosphorylated serine 27 at and around the N-terminal region of histone H1.B.
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Molecular Weight:
35 kDa
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Epitope:
Phosphorylated H1.B (Ser27)
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Immunogen:
KLH-conjugated synthetic linear peptide corresponding to the region at and around phosphorylated serine 27 of histone H1.B.
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Modifications:
Phosphorylation
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Background Information:
Histones are highly conserved proteins that serve as the structural scaffold for the organization of nuclear DNA into chromatin. The four core histones, H2A, H2B, H3, and H4, assemble into an octamer (2 molecules of each). Subsequently, 146 base pairs of DNA are wrapped around the octamer, forming a nucleosome. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into 30nm chromatin fibers and higher order structures.
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Species Reactivity:
Human
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Species Reactivity Note:
Human
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Control:
Untreated and colcemid-treated HeLa acid extract.
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Quality Assurance:
Evaluated by western blot on untreated and colcemid-treated HeLa acid extract.Western Blotting Analysis: 0.1 µg/mL of this antibody detected phospho-Histone H1.B (Ser27) in untreated and colcemid-treated HeLa acid extract.
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Purification Method:
Affinity Purfied
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Presentation:
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl, and 0.05% sodium azide.
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Storage Conditions:
Stable for 1 year at 2-8ºC from date of receipt.
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UniProt Number:
P16403
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Entrez Gene Number:
NP_005310
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Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Key Applications:
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Western Blotting
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Multiplexing
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Product Name:
Anti-phospho-Histone H1.B (Ser27)
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Concentration:
0.5 mg/mL
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Antibody Type:
Polyclonal Antibody
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Qty/Pk:
100 ug
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Format:
Purified
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Host:
Rabbit
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