金山科研平台，产品价格货期咨询微信：jinshanbio Source:Chinese Hamster Ovary cell line, CHO-derived, Gln26-Gln900, with a C-terminal 10-His tag Accession #:Q9R1B9 N-terminal Sequence Analysis:No results obtained; Gln26 predicted Purity:>85%, by SDS-PAGE under reducing conditions and visualized by silver stain. Predicted Molecular Mass:99.7 kDa SDS-PAGE:105-115 kDa, reducing conditions Activity:Measured by its ability to enhance neurite outgrowth of dissociated E13 chick embryonic dorsal root ganglia (DRG) neurons. Recombinant Mouse Slit2 immobilized at 3 - 12 µg/mL, is able to significantly induce neurite outgrowth. Formulation:Lyophilized from a 0.2 µm filtered solution in MOPS and NaCl.See Certificate of Analysis for details. Molecule Information: Slit2 Long Name: SLIT Homolog 2 Aliases: SLIL3 Entrez Gene IDs: 9353 (Human); 20563 (Mouse); 360272 (Rat) Background: Slit Ligands & ROBO Receptors Members of the ROBO family are a group of highly conserved transmembrane glycoproteins that make up a small subgroup of the immunoglobulin (Ig) superfamily. They are characterized structurally by five C2-type Ig-like repeats, three fibronectin type III domains, a transmembrane region, and an intracellular domain with three (ROBO3) or four (ROBO1, 2) CC (conserved cytoplasmic) motifs. ROBO4, a fourth putative family member, has been identified, but lacks one of the three fibronectin-like domains and two of the five Ig-like domains. ROBOs are best known for their roles as receptors for the Slit family of repellent axon guidance cues.