金山科研平台，产品价格货期咨询微信：jinshanbio Source:Spodoptera frugiperda, Sf 21 (baculovirus)-derived, Met1-Ile417, with an C-terminal 10-His tag Accession #:P00558 N-terminal Sequence Analysis:No results obtained Purity:>95%, by SDS-PAGE under reducing conditions and visualized by silver stain. Endotoxin Level: Predicted Molecular Mass:46 kDa SDS-PAGE:42 kDa, reducing conditions Activity:Measured by NADH production in a reaction coupled with GAPDH.The specific activity, as measured under the described condtions, is >50,000 pmol/min/µg. Formulation:Supplied as a 0.2 µm filtered solution in Tris, NaCl and Glycerol.See Certificate of Analysis for details. Molecule Information: PGK1 Long Name: Phosphoglycerate Kinase-1 Aliases: MIG10; PGKA; PRP2 Entrez Gene IDs: 5230 (Human); 18655 (Mouse); 24644 (Rat) Background: PGK1 Phosphoglycerate kinase-1 (PGK1) is a glycolytic enzyme that catalyzes the conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate. The gene encoding PGK1 is X-linked. Mutations of this gene may cause phosphoglycerate kinase deficiency, which is characterized by hemolytic anemia, muscle stiffness and mental retardation. PGK1 is induced by oxidative stress through the induction of hypoxia-inducible factor 1a and is a potential biomarker and therapeutic target for cancer.