R&D Systems代理5496-MF-050 Recombinant Mouse FGF R2 alpha (IIIb) Fc Chimera Protein, CF (50 UG)-试剂-金山科研平台

R&D Systems代理5496-MF-050 Recombinant Mouse FGF R2 alpha (IIIb) Fc Chimera Protein, CF (50 UG)

2025-06-27

货号：5496-MF-050

品牌：R&D Systems

规格：50ug

目录价：￥4490.00

市场价格：￥3592.00

会员价格：￥3592.00

到货时间：3~4周

金山科研平台，产品价格货期咨询微信：jinshanbio Source:Mouse myeloma cell line, NS0-derived Accession #:ABL89196 N-terminal Sequence Analysis:Arg22, Ser24, and Leu27 Structure:Disulfide-linked homodimer Purity:>90%, by SDS-PAGE under reducing conditions and visualized by silver stain. Predicted Molecular Mass:66.2 kDa (monomer) SDS-PAGE:105-120 kDa, reducing conditions Activity:Measured by its binding ability in a functional ELISA.

200 ng/mL of biotinylated rmFGF1 is mixed with serially diluted rmFGF R2 alpha (IIIb)/Fc. Following incubation, the FGF R2 alpha (IIIb)/Fc - FGF1/biotin complex is captured on a Streptavidin coated plate (R&D Systems, Catalog# CP003). Bound FGFR2 alpha (IIIb)/Fcis measured using HRP labeled Gt x Human IgG Fc. The concentration of rmFGFR2 alpha (IIIb)/Fc that produces 50% of the optimal binding was found to be approximately150 -600 ng/mL.

Formulation:Lyophilized from a 0.2 µm filtered solution in PBS.See Certificate of Analysis for details. Molecule Information: FGF R2 alpha Long Name: Fibroblast Growth Factor Receptor 2 alpha Entrez Gene IDs: 2263 (Human); 14183 (Mouse) Background: FGF Receptors FGF activity is mediated by a family of type I transmembrane tyrosine kinases, which undergo dimerization and autophosphorylation after ligand binding. Five distinct genes encode closely related FGF receptors, FGF R1 through 5. FGF Rs contain three Ig-like domains and a stretch of acidic residues between the first and second Ig-like domains. FGF R1, 2, 3, and -4 have a cytoplasmic split tyrosine-kinase domain, but FGF R5 does not. Multiple forms of FGF R1, 2, and 3 are generated by alternative splicing

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