货号：12-131

品牌：Merck Millipore

规格：EA

目录价：￥3920.00

市场价格：￥3332.00

会员价格：￥3136.00

金山科研平台，产品价格货期咨询微信：jinshanbio Description: IGFBP-3 View All» Trade Name: Upstate (Millipore) View All» Qty/Pk: 5 µg View All» Key Applications: Affinity Binding Assay View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Entrez Gene Summary: This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. View All» UniProt Summary: FUNCTION: SwissProt: P17936 # IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.SIZE: 291 amino acids; 31674 Da SUBUNIT: Interacts with XLKD1 (By similarity). Binds IGF2 more than IGF1. Forms a ternary complex of about 140 to 150 kDa with IGF1 or IGF2 and a 85 kDa glycoprotein (ALS). Interacts with HN.SUBCELLULAR LOCATION: Secreted.TISSUE SPECIFICITY: Expressed by most tissues.DEVELOPMENTAL STAGE: IGFBP3 levels are higher during extrauterine life and peak during puberty.DOMAIN: SwissProt: P17936 The thyroglobulin type-1 domain mediates interaction with HN.SIMILARITY: Contains 1 IGFBP N-terminal domain. & Contains 1 thyroglobulin type-1 domain. View All» Species: Human View All» Brand Family: Upstate View All» Presentation: Lyophilized powder View All» Storage Conditions: Lyophilized: 2 years at 4°C. Rehydrated: 1 year at -20°C. View All» Gene Symbol:

• IGFBP3

• IBP3

• IGFBP-3

• BP-53
  View All» Product Name: IGFBP-3 View All» Quality Assurance: Routeinly evaluated in a binding activity assay by binding IGF-I. View All» UniProt Number: P17936 View All» Entrez Gene Number:
  • NM_000598.4

  • NM_001013398.1
    View All»
    © 金山科研平台是专业的授权总代理区域代理经销平台。
    © 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
    © 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
    © 本文地址：https://www.16ao.com/thread-137123.htm
    © Merck Millipore代理12-131 HU IGF BP3,RECOMBINANT 5UG，产品报价联系微信jinshanbio