R&D Systems代理5684-AO-020 Recombinant Human IL-4I1 Protein, CF (20 UG)

2025-06-27

货号:5684-AO-020

品牌:R&D Systems

规格:20ug

目录价:¥4900.00

市场价格:¥3920.00

会员价格:¥3920.00

  • 到货时间:3~4周

    金山科研平台,产品价格货期咨询微信:jinshanbio Source:Chinese Hamster Ovary cell line, CHO-derived, Gln22-His567, with a C-terminal 6-His tag Accession #:Q96RQ9 N-terminal Sequence Analysis:No results obtained: Gln22 predicted Structure:Monomer Purity:>95%, by SDS-PAGE under reducing conditions and visualized by silver stain. Endotoxin Level: Predicted Molecular Mass:61 kDa SDS-PAGE:70-75 kDa, reducing conditions Activity:Measured by its ability to oxidize phenylalanine in a horseradish peroxidase coupled assay.The specific activity is >150 pmol/min/µg, as measured under the described conditions. Formulation:Supplied as a 0.2 µm filtered solution in Tris, NaCl and Glycerol.See Certificate of Analysis for details. Molecule Information: IL-4I1 Long Name: Interleukin 4-induced Protein-1 Aliases: FIG1 Entrez Gene IDs: 259307 (Human); 14204 (Mouse); 308575 (Rat) Background: IL-4I1 Interleukin 4 induced protein 1 (IL-4I1), also known as protein FIG-1 and L-amino acid oxidase, is encoded by a B-cell IL-4-inducible gene, FIG1, and is highly expressed in primary metastinal B-cell lymphomas. It belongs to the flavin monoamine oxidase family, FIG1 subfamily. Enzymological characterization reveals that IL-4I1 has L-amino acid oxidase activity with preference toward aromatic amino acids. Studies have shown that hIL-4I1 inhibited the proliferation of CD3-stimulated T lymphocytes with a similar effect on CD4(+) and CD8(+) T cells. Its inhibitory effect was dependent on enzymatic activity and H2O2 production. Its restricted expression to lymphoid tissues indicates that it may play an important function in the immune system.

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