金山科研平台，产品价格货期咨询微信：jinshanbio Source:Chinese Hamster Ovary cell line, CHO-derived, Tyr23-Met189, with a C-terminal 6-His tag Accession #:Q03431 N-terminal Sequence Analysis:Tyr23 Purity:>95%, by SDS-PAGE under reducing conditions and visualized by silver stain. Predicted Molecular Mass:20.0kDa SDS-PAGE:25-40 kDa, redicomg conditons Activity:Measured by its binding ability in a functional ELISA. WhenrhPTH1Ris used at2µg/mL, the concentration ofbiotinylated human PTHrP that produces 50% of the optimal binding responseis found to be approximately0.03‑0.12 µg/mL Formulation:Lyophilized from a 0.2 µm filtered solution in PBS.See Certificate of Analysis for details. Molecule Information: PTH1R/PTHR1 Long Name: Parathyroid Hormone Receptor 1 Aliases: PTHR; PTHR1 Entrez Gene IDs: 5745 (Human); 19228 (Mouse); 56813 (Rat) Background: PTH1R PTH1R (parathyroid receptor-1) is a 7-transmembrane receptor that expressed in bone, kidney and other tissues where its ligands, PTH (parathyroid hormone) and PTHrP (PTH-related protein), are found. Both gain and loss of function are associated with dwarfism in Jansen-type metaphyseal chondrodysplasia, or Blomstrand chondrodysplasia, respectively. Impaired function may be a factor in developmental endochondromas in Ollier disease. Polymorphisms may also be associated with variation in bone mineral density.