R&D Systems代理581-CR-010 Recombinant Cotton Rat IL-10 (Cys149Tyr) Protein (10 UG)-试剂-金山科研平台

R&D Systems代理581-CR-010 Recombinant Cotton Rat IL-10 (Cys149Tyr) Protein (10 UG)

2025-06-25

货号：581-CR-010

品牌：R&D Systems

规格：10ug

目录价：￥4080.00

市场价格：￥3264.00

会员价格：￥3264.00

到货时间：3~4周

金山科研平台，产品价格货期咨询微信：jinshanbio Source:E. coli-derived, Ser1-Ser160 (Cys149Tyr) Accession #:AAK94013 N-terminal Sequence Analysis:Ser1 Structure:Noncovalently-linked homodimer Purity:>97%, by SDS-PAGE under reducing conditions and visualized by silver stain. Endotoxin Level: Predicted Molecular Mass:18.7 kDa (monomer) Activity:Measured in a cell proliferation assay using MC/9‑2 mouse mast cells. Thompson-Snipes, L.et al. (1991) J. Exp. Med. 173:507.The ED₅₀ for this effect is typically 0.04‑0.24ng/mL. Molecule Information: IL-10 Long Name: Interleukin 10 Aliases: CSIF Entrez Gene IDs: 3586 (Human); 16153 (Mouse); 25325 (Rat); 397106 (Porcine); 403628 (Canine); 493683 (Feline); 100135553 (Guinea Pig); 2949786 (Viral) Background: IL-10

View IL-10 IHC images. Interleukin 10 (IL-10), initially designated cytokine synthesis inhibitory factor (CSIF), was originally identified as a product of mouse T helper (Th) 2 clones that inhibited cytokine production by Th1 clones . The human ortholog of mouse IL-10 was subsequently cloned by cross-hybridization. Human and mouse IL-10 are 81% identical at the nucleotide and amino acid level. IL-10 is the prototypic member of the IL-10 cytokine family, including IL-10, IL-19, IL-20, IL-22 (IL-TIF), IL-24 and IL-26. A number of viruses, including Epstein-Barr virus (EBV) and human cytomegalovirus (HCMV), also encode viral members of the IL-10 family. Human IL-10 has cross-species actvity and is active on mouse cells. Mouse IL-10 is species-specific and does not act on human cells.

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