R&D Systems代理5868-AR-010 Recombinant Human Arginase 1/ARG1 Protein, CF (10 UG)

2025-06-29

货号:5868-AR-010

品牌:R&D Systems

规格:10ug

目录价:¥4490.00

市场价格:¥3592.00

会员价格:¥3592.00

  • 到货时间:3~4周

    金山科研平台,产品价格货期咨询微信:jinshanbio Source:E. coli-derived, Met1-Lys322 with an N-terminal Met and 6-His tag Accession #:P05089 N-terminal Sequence Analysis:Met Structure:Monomer Purity:>90%, by SDS-PAGE under reducing conditions and visualized by silver stain. Endotoxin Level: Predicted Molecular Mass:36 kDa SDS-PAGE:40 kDa, reducing conditions Activity:Measured by the production of urea during the hydrolysis of arginine.The specific activity is >35,000 pmol/min/µg, as measured under the described conditions. Formulation:Supplied as a 0.2 µm filtered solution in Tris, NaCl, Glycerol and DTT.See Certificate of Analysis for details. Molecule Information: Arginase 1/ARG1 Aliases: ARG1 Entrez Gene IDs: 383 (Human) Background: Arginase 1 Arginase 1, also known as liver arginase, is a binuclear manganese metalloenzyme. It is a key enzyme of the urea cycle that catalyses the conversion of L-arginine into L-ornithine and urea, the final cytosolic reaction of urea formation in the mammalian liver. Arginase 1 is abundantly expressed in liver, but it is also expressed in cells and tissues that lack a complete urea cycle, including lung. Arginase is a critical regulator of nitric oxide synthesis and vascular function. It is implicated in a variety of human diseases including vascular disease, pulmonary disease, infectious disease, immune cell function and cancer. In humans, hereditary defects in arginase result in an accumulation of arginine in the blood known as hyperarginemia. Arginase deficiency can also result in the accumulation of nitrogen in the form of ammonia, which results in hyperammonemia.

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