R&D Systems代理5890-CN-050 Recombinant Mouse Contactin-6 Protein, CF (50 UG)-试剂-金山科研平台

R&D Systems代理5890-CN-050 Recombinant Mouse Contactin-6 Protein, CF (50 UG)

2025-06-27

货号：5890-CN-050

品牌：R&D Systems

规格：50ug

目录价：￥4490.00

市场价格：￥3592.00

会员价格：￥3592.00

到货时间：3~4周

金山科研平台，产品价格货期咨询微信：jinshanbio Source:Chinese Hamster Ovary cell line, CHO-derived, Glu20-Ser998, with a C-terminal 6-His tag Accession #:Q9JMB8 N-terminal Sequence Analysis:Glu20 Purity:>95%, by SDS-PAGE under reducing conditions and visualized by silver stain. Predicted Molecular Mass:109.2 kDa SDS-PAGE:140-160 kDa, reducing conditions Activity:Measured by the ability of the immobilized protein to support the adhesion of Neuro‑2A mouse neuroblastoma cells.

When5 x 10⁴ cells/well are added to rmContactin-6 coated plates (10 µg/mL, 100µL/well), approximately 40-60% will adhere after 30 minutes at 37 °C.

Optimal dilutions should be determined by each laboratory for each application.

Formulation:Lyophilized from a 0.2 µm filtered solution in PBS.See Certificate of Analysis for details. Molecule Information: Contactin-6 Aliases: CNTN6; NB3 Entrez Gene IDs: 27255 (Human); 53870 (Mouse); 27256 (Rat) Background: Contactin-6 Contactin-6, also known as NB-3, is a GPI-linked protein that is differentially expressed within various structures of the brain. In the cerebellum, it is presynaptically localized at synapses between excitatory glutamatergic parallel fibers and Purkinje cells. Contactin-6 knockout mice exhibit poor motor coordination. Contactin-6 associates in cis with CHL-1 and in trans with Notch-1 on oligodendrocytes. Its binding to Notch-1 triggers translocation of the Notch intracellular domain to the nucleus and promotes oligodendrogenesis.

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