货号：12-491

品牌：Merck Millipore

规格：EA

目录价：询价

金山科研平台，产品价格货期咨询微信：jinshanbio Description: ACC2 (aa 175-271) View All» Trade Name: Upstate (Millipore) View All» Qty/Pk: 1 mg View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Entrez Gene Summary: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. ACC-beta is thought to control fatty acid oxidation by means of the ability of malonyl-CoA to inhibit carnitine-palmitoyl-CoA transferase I, the rate-limiting step in fatty acid uptake and oxidation by mitochondria. ACC-beta may be involved in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. There is evidence for the presence of two ACC-beta isoforms. View All» UniProt Summary: FUNCTION: SwissProt: O00763 # ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase.COFACTOR: Biotin (By similarity). & Binds 2 manganese ions per subunit (By similarity).SIZE: 2458 amino acids; 276555 Da SUBCELLULAR LOCATION: Intracytoplasmic membrane. Note=May associate with membranes.TISSUE SPECIFICITY: Predominantly expressed in the heart, skeletal muscles and liver.SIMILARITY: SwissProt: O00763 ## Contains 1 ATP-grasp domain. & Contains 1 biotin carboxylation domain. & Contains 1 biotinyl-binding domain. & Contains 1 carboxyltransferase domain. View All» Species: Human View All» Quality Assurance: Routinely evaluated for use as a substrate in a kinase assay. View All» Brand Family: Upstate View All» Presentation: 50mM Tris-HCl, pH 8.0, 150mM NaCl, and 20mM glutathione, before the addition of glycerol to 20% View All» UniProt Number: O00763 View All» Storage Conditions: 1 year at -20°C View All» Gene Symbol:

• ACACB

• ACC2

• ACCB

• ACC-beta

• HACC275
  View All» Product Name: ACC2 (aa 175-271) View All» Entrez Gene Number: NM_001093.3 View All»
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