金山科研平台，产品价格货期咨询微信：jinshanbio Source:Chinese Hamster Ovary cell line, CHO-derived, Met1-Ile753, with a C-terminal 10-His tag Accession #:P58215 N-terminal Sequence Analysis:Ser26 Structure:Monomer Purity:>90%, by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie® Blue stain at 5 µg per lane. Endotoxin Level: Predicted Molecular Mass:82 kDa SDS-PAGE:90-100 kDa, reducing conditions Activity:Measured by its ability to produce hydrogen peroxide during the oxidation of benzylamine.The specific activity is >1.5 pmol/min/µg, as measured under the described conditions. Formulation:Supplied as a 0.2 µm filtered solution in MES and NaCl.See Certificate of Analysis for details. Molecule Information: Lysyl Oxidase Homolog 3/LOXL3 Aliases: LOL3; LOXL3 Entrez Gene IDs: 84695 (Human) Background: Lysyl Oxidase Homolog 3 Lysyl oxidase-like protein 3 (LOXL3) is a secreted copper amine oxidase. The N-terminal region of LOXL3 contains four scavenger receptor cysteine-rich (SRCR) domains. The C-terminal region consists of a catalytic domain similar to other lysyl oxidases and a cytokine receptor-like domain. The catalytic domain contains conserved residues required for copper binding and formation of a lysyl tyrosylquinone cofactor. LOXL3 is expressed primarily in epidermis, kidney, aorta, and chondrocytes. The enzyme is expressed at low levels in most other tissues. Like lysyl oxidase, LOXL3 oxidizes the lysine e-amino groups of a number of collagen substrates, and is also active against other primary amines. However, LOXL3 does not require proteolytic processing to be activated.