R&D Systems代理6150-ME-050 Recombinant Mouse MEPE/OF45 Protein, CF (50 UG)-试剂-金山科研平台

R&D Systems代理6150-ME-050 Recombinant Mouse MEPE/OF45 Protein, CF (50 UG)

2025-06-28

货号：6150-ME-050

品牌：R&D Systems

规格：50ug

目录价：￥4490.00

市场价格：￥3592.00

会员价格：￥3592.00

到货时间：3~4周

金山科研平台，产品价格货期咨询微信：jinshanbio Source:Mouse myeloma cell line, NS0-derived, Met1-Asp433, with a C-terminal 10-His tag Accession #:AAK70342 N-terminal Sequence Analysis:Ser147 Purity:>95%, by SDS-PAGE under reducing conditions and visualized by silver stain. Predicted Molecular Mass:31.6 kDa SDS-PAGE:40-55 kDa, reducing conditions Activity:Measured by its ability to induce adhesion of ATDC5 mouse chondrogenic cells.

The ED₅₀ for this effect is typically 0.1 - 0.4 µg/mL.

Optimal dilutions should be determined by each laboratory for each application.

Formulation:Lyophilized from a 0.2 µm filtered solution in PBS.See Certificate of Analysis for details. Molecule Information: MEPE/OF45 Long Name: Matrix Extracellular Phosphoglycoprotein with ASARM Motif Aliases: OF45; Osteoregulin Entrez Gene IDs: 56955 (Human); 94111 (Mouse); 79110 (Rat) Background: MEPE MEPE, known as OF45 in mouse and rat, is a 55 kDa member of the SIBLING protein family that is primarily expressed in bone and dentin where it regulates the mineralization of those tissues. MEPE is secreted by osteoblasts and dental pulp stem cells during the mineralization process and also by non-mineralizing tissues including epithelial cells in the renal proximal tubule and salivary duct. MEPE contains multiple consensus sites for post-translational modifications, including N-linked glycosylation, N-myristoylation, glycosaminoglycan attachment, and phosphorylation by a variety of kinases. MEPE also contains several putative proteolytic cleavage sites and one integrin-binding RGD motif.

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