金山科研平台，产品价格货期咨询微信：jinshanbio Source:E. coli-derived, Thr23-Gly117 Accession #:AAA85885 N-terminal Sequence Analysis:Thr23 Purity:>97%, by SDS-PAGE under reducing conditions and visualized by silver stain. Predicted Molecular Mass:11.1 kDa Activity:Measured by its ability to induce myeloperoxidase release from cytochalasin B-treated human neutrophils. Schröder, J.M. etal. (1987) J.Immunol. 139:3474.The ED₅₀ for this effect is typically 0.3 - 0.6 µg/mL.Measured by its ability to chemoattract BaF3 mouse pro‑B cells transfected with human CXCR2.The ED₅₀ for this effect is typically 0.03 - 0.18 µg/mL. Molecule Information: UL146/vCXC1 Long Name: Cytomegalovirus UL146 Aliases: HHV5wtgp117; vCXC1; vCXCL1; Y18 Background: CMV UL146 & CMV UL147 Cytomegalovirus (CMV), a member of the beta herpesvirus subfamily, typically causes subclinical or latent infections in the normal adult population. However, CMV can cause congenital disease during pregnancy and is a human opportunistic pathogen that affects immunocompromised individuals. Virulent CMV clinical isolates have also been shown to carry at least 19 genes, designated UL133 - UL151, that are not found in laboratory strains that have lost virulence characteristics. Two of these genes, UL146 and UL147, exhibit sequence similarity to CXC chemokines.