金山科研平台，产品价格货期咨询微信：jinshanbio Source:Mouse myeloma cell line, NS0-derived Accession #:P09758.3 N-terminal Sequence Analysis:Thr88 Structure:Disulfide-linked homodimer Purity:>95%, by SDS-PAGE under reducing conditions and visualized by silver stain. Predicted Molecular Mass:49.2 kDa (monomer) SDS-PAGE:70-80 kDa, reducing conditions Activity:Measured by the ability of the immobilized protein to support the adhesion of U937 human histiocytic lymphoma cells or LS180 human colorectal adenocarcinoma cells.When 1 x 10⁴ to 5 x 10⁴cells/well are added to Recombinant Human TROP‑2 Fc Chimera coated plates (10µg/mL with 100µL/well),>45%cells will adhere after 1hour incubation.Optimal dilutions should be determined by each laboratory for each application. Formulation:Lyophilized from a 0.2 µm filtered solution in PBS.See Certificate of Analysis for details. Molecule Information: TROP-2 Long Name: Tumor-associated Calcium Signal Transducer 2 Aliases: GA733-1; gp50; T16; TACSTD2 Entrez Gene IDs: 4070 (Human); 56753 (Mouse) Background: TROP-2 Human TROP-2, also called tumor associated calcium signal transducer 2 (TACSTD2), gp50 and T16, is a type I cell surface glycoprotein that is highly expressed on human carcinomas. It is related to EpCAM, also called TROP-1, gp40 and KSA. A study of these two genes suggests that TROP-2 was generated through the retropositioning of the EpCAM gene. TROP-2 and EpCAM share approximately 49% amino acid sequence identity and approximately 67% similarity. Mature human and mouse TROP-2 share 80% amino acid identity.