金山科研平台，产品价格货期咨询微信：jinshanbio Source:Mouse myeloma cell line, NS0-derived Accession #:O70458 N-terminal Sequence Analysis:Glu24 Structure:Disulfide-linked homodimer Purity:>90%, by SDS-PAGE under reducing conditions and visualized by silver stain. Endotoxin Level: Predicted Molecular Mass:109 kDa (monomer) SDS-PAGE:120-150 kDa, reducing conditions Activity:Measured by its binding ability in a functional ELISA.When Recombinant Mouse OSMR beta FcChimera is immobilized at0.5µg/mL and Recombinant Mouse gp130FcChimera (Catalog# 468-MG) at 0.5µg/mL (100µL/well), the concentration of Recombinant Mouse OncostatinM/OSM (Catalog# 495-MO) that produces 50%of the optimal binding response is approximately 0.2‑1ng/mL. Formulation:Lyophilized from a 0.2 µm filtered solution in PBS.See Certificate of Analysis for details. Molecule Information: OSM R beta Long Name: Oncostatin M Receptor beta Aliases: OSMR; OSMRB Entrez Gene IDs: 9180 (Human); 18414 (Mouse); 310132 (Rat) Background: Oncostatin M Receptor beta Human Oncostatin M (OSM) signals through two types of human OSM receptor complexes: the type I complex comprising the leukemia inhibitory factor receptor beta (LIF R beta) and gp130 and the type II complex made up of OSM receptor beta (OSM R beta) and gp130. In contrast, mouse OSM signals only through the mouse OSM R beta and gp130 complex. Human and mouse OSM R beta are 55% identical at the amino acid sequence level.