R&D Systems代理6637-RN-025 Recombinant Mouse Relaxin-1 Protein (25 UG)-试剂-金山科研平台

R&D Systems代理6637-RN-025 Recombinant Mouse Relaxin-1 Protein (25 UG)

2025-06-27

货号：6637-RN-025

品牌：R&D Systems

规格：25ug

目录价：￥4490.00

市场价格：￥3592.00

会员价格：￥3592.00

到货时间：3~4周

金山科研平台，产品价格货期咨询微信：jinshanbio Source:E. coli-derived, Arg23-Arg54, with an N-terminal Met (B chain) & Glu161-Cys185 (A chain) Accession #:NP_035402 N-terminal Sequence Analysis:Met (B chain) & Glu161 (A chain) Structure:Disulfide-linked heterodimer Purity:>95%, by SDS-PAGE under reducing conditions and visualized by silver stain. Predicted Molecular Mass:3.9 kDa (B chain) & 2.7 kDa (A chain) SDS-PAGE:4&3 kDa, reducing conditions Activity:Measured by its ability to induce cAMP accumulation in THP‑1 human acute monocytic leukemia cells. Parsell, D.A. et al. (1996) J. Biol. Chem. 271:27936.

The ED₅₀ for this effect is typically 2 - 8 ng/mL.

Molecule Information: Relaxin-1 Aliases: H1; RLN1; RLXH1 Entrez Gene IDs: 6013 (Human); 19773 (Mouse); 25616 (Rat) Background: Relaxins The Insulin/Relaxin superfamily includes Insulin, IGF-I, IGF-II, Relaxins, Relaxin-like Factor (RLF), Early Placenta Insulin-like Peptide 4 (INSL4), INSL5, and INSL6. Three human Relaxin genes (Relaxins-1 to -3) have been identified. Relaxin-2 is secreted and circulates in the blood, whereas Relaxin-1 is expressed in decidua, placenta, and prostate, and Relaxin-3 is expressed in the brain. Human Relaxin-2 is a peptide hormone that plays an important role in female reproduction.

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