R&D Systems代理6795-PR-050 Recombinant Human Protogenin Protein, CF (50 UG)-试剂-金山科研平台

R&D Systems代理6795-PR-050 Recombinant Human Protogenin Protein, CF (50 UG)

2025-06-27

货号：6795-PR-050

品牌：R&D Systems

规格：50ug

目录价：￥4490.00

市场价格：￥3592.00

会员价格：￥3592.00

到货时间：3~4周

金山科研平台，产品价格货期咨询微信：jinshanbio Source:Mouse myeloma cell line, NS0-derived, Phe36-Ala952, with a C-terminal 6-His tag Accession #:NP_776175 N-terminal Sequence Analysis:Phe36 Purity:>95%, by SDS-PAGE under reducing conditions and visualized by silver stain. Predicted Molecular Mass:102.7 kDa SDS-PAGE:120-130 kDa, reducing conditions Activity:Measured by the ability of the immobilized protein to support the adhesion of P19 mouse embryonal carcinoma cells.

When 5 x 10⁴ cells per well are added to Recombinant Human Protogenin coated plates, cell adhesion is enhanced in a dose dependent manner. The ED₅₀ for this effect is typically2 - 8µg/mL.

Optimal dilutions should be determined by each laboratory for each application.

Formulation:Lyophilized from a 0.2 µm filtered solution in PBS.See Certificate of Analysis for details. Molecule Information: Protogenin Aliases: IGDCC5; PRTG; RPTG; Shen-Dan Entrez Gene IDs: 283659 (Human); 235472 (Mouse); 315806 (Rat) Background: Protogenin View Protogenin IHC images. Protogenin (Early/proto in expression, neogenin-like; also Prtg) is a 130 kDa (predicted), type I transmembrane member of the DCC/Neogenin family of proteins. It is expressed in mouse presomitic mesoderm, paraxial mesoderm, and neural tube. Mature mouse protogenin is 1168 amino acids (aa) in length. It contains a 920 aa extracellular domain (ECD) (aa 24 - 943) plus a 224 aa cytoplasmic region. The ECD contains four consecutive Ig-like domains (aa 24 - 405), followed by five sequential fibronectin type III domains (aa 413 - 908). The ECD of mouse protogenin shares 98%, 87% and 93% aa identity with the ECD of rat, chick and human protogenin, respectively.

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