金山科研平台，产品价格货期咨询微信：jinshanbio Source:Mouse myeloma cell line, NS0-derived Accession #:Q9Y6Q6.1 N-terminal Sequence Analysis:Met Structure:Disulfide-linked homodimer Purity:>95%, by SDS-PAGE under reducing conditions and visualized by silver stain. Predicted Molecular Mass:48 kDa (monomer) SDS-PAGE:60 kDa, reducing conditions Activity:Measured by its ability to inhibit TRANCE-induced osteoclast differentiation of RAW264.7 mouse monocyte/macrophage cells.The ED₅₀ for this effect is typically 0.005-0.035µg/mL in the presence of2ng/mL of rmTRANCE (R&D Systems, Catalog# 462-TEC). Formulation:Lyophilized from a 0.2 µm filtered solution in PBS.See Certificate of Analysis for details. Molecule Information: RANK/TNFRSF11A Long Name: Receptor Activator of NF-kappa-B Aliases: CD265; ODFR; TNFRSF11A; TRANCE R Entrez Gene IDs: 8792 (Human); 21934 (Mouse) Background: RANK/TNFRSF11A View RANK IHC images. Receptor activator of NF-kB (RANK), also known as TRANCE receptor, osteoclast differentiation factor receptor (ODFR) and TNFRSF11A, is a member of the TNF receptor superfamily. Human and mouse RANK share 81% amino acid sequence identity in their extracellular domains. RANK is widely expressed with highest levels in skeletal muscle, thymus, liver, colon, small intestine and adrenal gland.