R&D Systems代理6835-IL-010/CF Recombinant Human IL-36 gamma/IL-1F9 (aa 18-169) Protein, CF (10 UG)-试剂-金山科研平台

R&D Systems代理6835-IL-010/CF Recombinant Human IL-36 gamma/IL-1F9 (aa 18-169) Protein, CF (10 UG)

2025-06-27

货号：6835-IL-010/CF

品牌：R&D Systems

规格：10ug

目录价：￥4490.00

市场价格：￥3592.00

会员价格：￥3592.00

到货时间：3~4周

金山科研平台，产品价格货期咨询微信：jinshanbio Source:E. coli-derived, Ser18-Asp169 Accession #:Q9NZH8 N-terminal Sequence Analysis:Ser18 Purity:>95%, by SDS-PAGE under reducing conditions and visualized by silver stain. Predicted Molecular Mass:17 kDa SDS-PAGE:17 kDa, reducing conditions Activity:Measured by its ability to induce IL-8 secretion in human preadipocytes. van Asseldonk, E.J. et al. (2010) Obesity 18:2234.

The ED₅₀ for for this effect is typically 3 - 15 ng/mL

Molecule Information: IL-36 gamma/IL-1F9 Long Name: Interleukin 36 gamma/Interleukin 1 Family 9 Aliases: IL-1 H1; IL1F9; IL-1rp2; IL36G Entrez Gene IDs: 56300 (Human); 215257 (Mouse); 499744 (Rat) Background: IL-36 gamma Interleukin 36 gamma (IL-36 gamma), also known as IL-1F9 and IL-1H1 is a member of the IL-1 family. IL-36 gamma is secreted when transfected into 293-T cells. Cells reported to express IL-36 gamma include Langerhans cells, keratinocytes/stratified squamos epithelium, chief cells, and parietal cells. The receptor for IL-36 gamma is reported to be a combination of IL-1 R6/IL-1 R rp2 and IL-1 R3/IL-1 R AcP. Recombinant IL-36 gamma has been shown to activate pathways involving NF-kappa B and MAPK in an IL-1 R6/IL-1 R rp2-dependent manner.

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