金山科研平台，产品价格货期咨询微信：jinshanbio Source:Chinese Hamster Ovary cell line, CHO-derived, Asp254-Arg372 Accession #:NP_001483 N-terminal Sequence Analysis:Asp254 Structure:Disulfide-linked homodimer Purity:>95%, by SDS-PAGE under reducing conditions and visualized by silver stain. Predicted Molecular Mass:12.6 kDa (monomer) SDS-PAGE:13 kDa, reducing conditions Activity:Measured by its ability to induce Smad2 phosphorylation in P19 mouse embryonal carcinoma cells. Mazerbourg, S. et al. (2004) Mol. Endocrinol. 18:653.50 ng/mL of Recombinant Human GDF‑1 can effectively induce Smad2 phosphorylation. Molecule Information: GDF-1 Long Name: Growth Differentiation Factor 1 Entrez Gene IDs: 2657 (Human); 14559 (Mouse) Background: Growth/Differentiation Factors (GDFs) Growth/differentiation factors (GDF-1 to GDF-15) are members of the BMP family of TGF-beta superfamily proteins. They are produced as inactive preproproteins which are then cleaved and assembled into active secreted homodimers. GDF dimers are disulfide-linked with the exception of GDF-3 and -9. GDF proteins are important during embryonic development, particularly in the skeletal, nervous, and muscular systems.