金山科研平台，产品价格货期咨询微信：jinshanbio Source:Mouse myeloma cell line, NS0-derived Accession #:NP_034964 N-terminal Sequence Analysis:Asn25 Structure:Disulfide-linked homodimer Purity:>95%, by SDS-PAGE under reducing conditions and visualized by silver stain. Predicted Molecular Mass:54.9 kDa (monomer) SDS-PAGE:66 kDa, reducing conditions Activity:Measured by its ability to inhibit rmGDF-8 activity in K562 human chronic myelogenous leukemia cells. Thies, R.S. et al. (2001) Growth Factors 18:251.The ED₅₀ for this effect is typically 0.03-0.15 µg/mL in the presence of 40 ng/mL of Recombinant Mouse GDF‑8/Myostatin. Molecule Information: GDF-8/Myostatin Long Name: Growth Differentiation Factor 8 Aliases: MSTN; Myostatin Entrez Gene IDs: 2660 (Human); 17700 (Mouse) Background: Growth/Differentiation Factors (GDFs) Growth/differentiation factors (GDF-1 to GDF-15) are members of the BMP family of TGF-beta superfamily proteins. They are produced as inactive preproproteins which are then cleaved and assembled into active secreted homodimers. GDF dimers are disulfide-linked with the exception of GDF-3 and -9. GDF proteins are important during embryonic development, particularly in the skeletal, nervous, and muscular systems.